Prof. Sima Rafati Seyedi Yazdi
Affiliation:
Professor of Medical Biotechnology, Pasteur Institute of Iran
Professor of Medical Biotechnology, Pasteur Institute of Iran
Leishmaniasis vaccines DNA/Protein & live-vector (prime–boost) Vaccine-delivery platforms (nanoparticles/OMV)
Three most impressive contributions
- DNA/Protein “cocktail” vaccines for leishmaniasis — Early, highly-cited protection studies in mice (L. major) and in a canine VL model using cysteine-proteinase antigens (CPA/CPB).
- Influential review on cancer-vaccine delivery systems — Widely cited Molecular Cancer article synthesizing physical/chemical delivery platforms (e.g., nanoparticles, microparticles) for therapeutic vaccines.
- Live recombinant Leishmania tarentolae vaccine approach / EV work — Development and evaluation of non-pathogenic live vectors and related immunology lines that informed candidate vaccines.